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HPMC CAS Number Certified Quality & Safety Data Sheets
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May . 07, 2025 18:59 Back to list

HPMC CAS Number Certified Quality & Safety Data Sheets


  • Overview of HPMC and its significance in industrial applications
  • Technical specifications and performance advantages
  • Comparative analysis of leading manufacturers
  • Customized solutions for diverse industry needs
  • Real-world application case studies
  • Regulatory compliance and safety standards
  • Future trends in HPMC CAS number utilization

HPMC CAS Number Certified Quality & Safety Data Sheets

(hpmc cas number)


Understanding HPMC CAS number and its industrial relevance

Hydroxypropyl Methyl Cellulose (HPMC), identified by CAS number 9004-65-3, is a cellulose-derived polymer widely used in pharmaceuticals, construction, and food industries. With a global market projected to grow at a CAGR of 6.8% from 2023 to 2030, demand for HPMC is driven by its solubility, thermal stability, and non-toxic properties. The E number E464 designation further validates its safety in food applications, making it a versatile additive across sectors.

Technical superiority of hydroxypropyl methyl cellulose

HPMC stands out due to its adjustable viscosity (5–200,000 mPa·s), gelation temperature (50–90°C), and pH stability (3–11). Third-party testing confirms 99.5% purity in pharmaceutical-grade HPMC, exceeding USP/Ph.Eur. standards. Its moisture retention capacity (≤5% loss at 25°C/60% RH) makes it ideal for dry-mix mortars, reducing cracking by 40% in construction materials.

Manufacturer comparison: Key performance metrics

Manufacturer Viscosity Range (mPa·s) Gel Temp (°C) Purity (%) Certifications
Manufacturer A 50–100,000 58–85 99.3 USP, FDA, REACH
Manufacturer B 10–200,000 52–90 99.6 ISO, Halal, Kosher
Manufacturer C 5–150,000 60–88 99.4 EP, GMP, NSF

Tailored formulations for sector-specific requirements

Customized HPMC solutions address unique challenges:

  • Pharma: Delayed-release tablets with 12-hour dissolution profiles
  • Construction: Tile adhesives with 30-minute open time
  • Food: Gluten-free baked goods with 20% extended freshness
Particle size distribution can be adjusted between 80–200 μm, while substitution levels (19–30% methoxyl, 4–12% hydroxypropoxyl) are optimized per application.

Documented success in commercial applications

A 2022 European pharma company achieved 18-month stability in enteric-coated tablets using HPMC CAS 9004-65-3, reducing production costs by 22%. In Asia, a cement manufacturer reported 35% fewer shrinkage cracks by incorporating 0.2% HPMC by weight. Food processors utilizing E464-grade HPMC increased shelf life of sauces by 40% without preservatives.

Compliance with international safety protocols

All HPMC grades meet:

  • FDA 21 CFR §172.874 (food)
  • EP 9.0 Monograph 0682 (pharma)
  • ASTM C387/C387M-17 (construction)
Residual solvents are maintained below 500 ppm, with heavy metal content ≤10 ppm as per ICH Q3D guidelines.

Innovations in HPMC CAS number applications

Recent advancements include temperature-sensitive HPMC hydrogels for drug delivery (patent US20230151234A1) and 3D-printable construction mortars with 0.4% HPMC content. Emerging markets show 12% annual growth in HPMC-based vegan capsules, while sustainable production methods have reduced energy consumption by 18% since 2020.


HPMC CAS Number Certified Quality & Safety Data Sheets

(hpmc cas number)


FAQS on hpmc cas number

Q: What is the CAS number for HPMC?

A: The CAS number for Hydroxypropyl Methylcellulose (HPMC) is 9004-65-3. It is a unique identifier for this specific chemical compound. This number is used globally for regulatory and safety documentation.

Q: Is the CAS number for Hydroxypropyl Methyl Cellulose the same as HPMC?

A: Yes, Hydroxypropyl Methylcellulose (HPMC) and HPMC refer to the same compound. Both share the CAS number 9004-65-3. This ensures consistency across scientific and industrial databases.

Q: What is the E number for HPMC?

A: The E number for HPMC is E464. It is classified as a food additive and thickener. This code is used in the EU for food safety and labeling purposes.

Q: How does the CAS number differ from the E number for HPMC?

A: The CAS number (9004-65-3) is a global chemical identifier, while the E number (E464) is specific to food additives in the EU. CAS numbers are used for technical documentation, whereas E numbers relate to food safety regulations.

Q: Can HPMC be identified by both CAS and E numbers in products?

A: Yes, HPMC is often labeled with its CAS number (9004-65-3) in technical contexts and E number (E464) in food applications. Both identifiers ensure accurate classification and compliance with regulations.


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