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Barium sulfate, a high-density, water-insoluble compound, is used as a contrast medium for X-ray examinations. When ingested or administered via enema, it coats the inner lining of the stomach, intestines, or other parts of the GI tract. Due to its radiopacity, barium sulfate absorbs X-rays more than the surrounding tissues, thus creating a sharp contrast that outlines the contours of the organ being examined.