Genotoxicity refers to the ability of a chemical substance to damage DNA , the genetic material of cells. As genotoxicity may lead to carcinogenic effects, it is essential to assess the potential genotoxic effect of a substance to conclude on its safety.
In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon. There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”
ZnSO4 – BaS ➔ BaSO4*ZnS
Overall, titanium dioxide is a valuable white pigment that plays a crucial role in many industries. Its unique properties and versatility make it an essential ingredient in a wide range of products, from paints and plastics to paper and personal care items. As technology continues to advance, the demand for titanium dioxide is expected to grow, driving further innovation and development in the industry.Lithopone is rather nontoxic, due to the insolubility of its components. It has been used in medicine as a radiocontrast agent. Lithopone is allowed to be in contact with foodstuffs in the US and Europe.[1]
It is also advisable to establish a strong and open line of communication with your chosen supplier. This will allow you to address any concerns or issues that may arise, and ensure that your needs and expectations are met. Building a positive and collaborative relationship with your supplier can help to strengthen the partnership and enhance overall productivity and performance.Variations of titanium dioxide are added to enhance the whiteness of paint, plastics, and paper products, though these variations differ from the food-grade ones for things we eat (1Trusted Source, 2Trusted Source).